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California Regional Multiple Listing Service

The multiple listing data appearing on this website, or contained in reports produced therefrom, is owned and copyrighted by California Regional Multiple Listing Service, Inc. ("CRMLS") and is protected by all applicable copyright laws. Information provided is for viewer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties the viewer may be interested in purchasing. All listing data, including but not limited to square footage and lot size is believed to be accurate, but the listing Agent, listing Broker and CRMLS and its affiliates do not warrant or guarantee such accuracy. The viewer should independently verify the listed data prior to making any decisions based on such information by personal inspection and/or contacting a real estate professional.

Based on information from California Regional Multiple Listing Service, Inc. as of the most recent time synced and /or other sources. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information

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Home / South San Francisco / 643 Grand Avenue
643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 643 Grand Avenue South San Francisco, CA 94080 View All Photos

$1,248,000

| Active

643 Grand Avenue

South San Francisco, CA 94080

1,630
Square Feet
3
Beds
4
Baths
0.08
Acres
3
Days on Market
ML82059314
MLS#
House
Structure
Residential
Zone
Contact
Listing OfficeChristie's International Real Estate Sereno

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Property Details
Cooling
1
Heating
Central
Bedrooms
3
Bathrooms
4.0
Full Baths
4
Stories
2
Acres
0.08
Square Feet
1630.0
Lot Size (sqft)
3500.0
Parking
1
Parking Spaces
2
Parking Type
Garage
Parking Garage Spaces
2.0
Property Type
Purchase
Property Subtype Additional
Single Family Residence
Year Built
1895
Foundation
Slab
Roof
Shingle
Sewer Information
Public Sewer
Utility Source
Public
School District
South San Francisco Unified
County
San Mateo
Region
South San Francisco
Zoning
RM0000
Original List Price
$1,248,000
MLS #
ML82059314
Property Subtype
SingleFamilyResidence
Parcel Number
012241120
MLS #
ML82059314
Date Listed
August 27, 2026
Address
643 Grand Avenue
Location
Legal

The multiple listing data appearing on this website, or contained in reports produced therefrom, is owned and copyrighted by California Regional Multiple Listing Service, Inc. ("CRMLS") and is protected by all applicable copyright laws. Information provided is for viewer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties the viewer may be interested in purchasing. All listing data, including but not limited to square footage and lot size is believed to be accurate, but the listing Agent, listing Broker and CRMLS and its affiliates do not warrant or guarantee such accuracy. The viewer should independently verify the listed data prior to making any decisions based on such information by personal inspection and/or contacting a real estate professional.

Based on information from California Regional Multiple Listing Service, Inc. as of the most recent time synced and /or other sources. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information

Provided By
Listed by Jill Penna (#ML5085880)
Listing Office: Christie's International Real Estate Sereno (#ML5033630)

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